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Although disseminated lupus erythematosus is a relatively uncommon disease , it has a predilection for young women during the childbearing age, and the association of lupu pregnancy should not be overlooked. The following case is noe in which pregnancy was complicated by S.L.E this 35 year old multiparous women (2-0-1-2), in amenorrhea 36 weeks, was admitted to our Hospital with complications of occipital headache, severe generalized edema and butterfly rash for 5 year she delivered her first baby at home without specific complications 7 years ago, second baby at our hospital with mild S.L.E manifestations 3 years ago, and third baby with pronounced S.L.E manifestations. Typical L.E cells were found in peripheral blood smear of mother, but not of fetus. During admission she was treated with diuretics, antihypertensive drugs and prednisolone, but no improvement was found until puerperal period. NOw she revealed good condition but sustained hypertension and microscopic hematuria.
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